Yahoo! Sideline is an Adobe AIR desktop application built with the Yahoo! User Interface Library (YUI). It allows users to monitor Twitter by creating and grouping custom queries by topics of interest. It's a great example of an HTML/CSS/Ajax based AIR app, and lots of details have been posted on the Yahoo! User Interface Blog.
Brian Kai has created CF_REF, a CFML reference application for iPhone.
[Via a post on the CFUnited blog].
Adobe and Facebook have just announced a new ActionScript 3 Client Library that can be used to build Facebook applications in Flash. The library is free and open source, and includes more than 60 new APIs designed to compliment current Facebook APIs to ensure seamless implementation. Details are now online at http://www.adobe.com/go/facebook.